Therapeutic Plasma Exchange (TPE)

For more info or to book an appointment: Call (303) 233-4247 or text (303) 378-9221

Reset your body's internal healing systems

Therapeutic Plasma Exchange (TPE) is an advanced, non-surgical procedure that gently removes plasma from your blood and replaces it with a clean, sterile solution. This process filters out harmful proteins, toxins, and inflammatory molecules—supporting your body’s internal balance, resilience, and overall wellness.

TPE is increasingly recognized for helping those with neurodegenerative, autoimmune, toxin, inflammation, and age-related issues.

A modern, non-invasive therapy
for comprehensive wellness

By cleansing the plasma and restoring balance to key biological systems, TPE can enhance detoxification, support cognitive health, and improve overall resilience. 

Healthy aging

Activates pro-longevity genes and rejuvenates immune function.

Cognitive support

May improve focus and slow cognitive decline.

Deep detoxification

Clears environmental toxins, heavy metals, and inflammatory proteins.

Symptom relief

Supports energy, clarity, and reduced inflammation, including long-COVID symptoms.

TPE supports your circulation at
its foundation

By cleansing the plasma and restoring balance to key biological systems, TPE can enhance detoxification, support cognitive health, and improve overall resilience. 

FDA-approved procedure used worldwide

Reduces the biological burden on the circulatory system

Supports systemic reset & overall resilience

Why plasma matters

Plasma is not just a transport fluid — it’s where many of the body’s circulating inflammatory molecules, immune complexes, and environmental toxicants reside. Over time, these factors can contribute to:

Therapeutic Plasma Exchange works upstream by physically removing a portion of these circulating factors, toxins, and metabolic byproducts rather than attempting to suppress downstream symptoms.

What to expect:
Your TPE experience

At Grossman Wellness Center, TPE is delivered with precision, comfort, and white-glove attention. Our expert team guides you through each step, ensuring you feel informed, supported, and at ease.

  1. Blood draw: Blood is collected through an IV catheter.
  2. Plasma separation: A medical device gently separates plasma from the blood cells.
  3. Plasma replacement: The removed plasma is replaced with an albumin-saline solution.
  4. Return: Cleaned blood is returned to the body.

Most sessions last 2–3 hours, and treatment plans are tailored to your individual health goals.

Concierge-level care at every appointment

Treatments are administered in a serene, private environment with advanced equipment and evidence-based protocols.

Your physician remains closely involved, monitoring your response, adjusting your plan, and ensuring every session is smooth, safe, and restorative.

Who is TPE for?

Our focus is precision, safety, and appropriate patient selection — using TPE when it meaningfully supports a larger plan for long-term health and resilience.

Individuals suffering from autoimmune & chronic inflammatory conditions

Individuals experiencing long COVID or other post-viral syndromes

People who notice early cognitive changes or memory concerns

Individuals with cardiometabolic or vascular risk factors

People with elevated inflammatory markers or high toxic burden based on history & testing

Those who are focused on reducing age-related inflammation

Frequently asked questions about
Therapeutic Plasma Exchange

While dietary or supplement-based detox plans support the body’s natural detoxification, TPE plasma exchange physically eliminates toxins, heavy metals, and pro-inflammatory proteins, providing faster and more noticeable results.

Yes, TPE can benefit individuals looking to enhance overall health and longevity, even without a specific diagnosis. TPE helps by improving aging-associated biomarkers, reducing inflammation, and supporting cellular health.

Yes, TPE may benefit skin conditions related to inflammation or toxin buildup, such as eczema, psoriasis, or acne. TPE can support healthier skin and reduce the severity of certain conditions.

While both TPE and apheresis involve separating blood components, TPE focuses on removing and replacing plasma to target harmful substances like toxins and inflammatory proteins. Apheresis, on the other hand, can involve removing other blood components, such as platelets or white blood cells, for different therapeutic purposes.

Interested in learning more at home?

Explore our book, "Plasma Reset: Change Your Blood, Change Your Life"

In Plasma Reset: Change Your Blood, Change Your Life, explore groundbreaking research that reveals how this remarkable procedure revitalizes your blood, reboots your cellular machinery, and emerges as one of the most potent anti-aging therapies available today.

Reach out for an appointment Curated care starts here

Whether it’s exploring one of our specialty programs or considering our innovative therapeutic plasma exchange, our team will curate a plan tailored to your biology and your goals.